BUY PRL-8-53 10MG
BUY PRL-8-53 - BEST PRL-8-53 FOR SALE ONLINE
- Dopamine agonist
- Serotonin inhibitor / Serotonin production
- Mental clarity - enhanced learning and subsequent retention in humans
- Memory enhancing, especially short term
- Suppresses anxiety
- Insomnia relief
- Neurotransmission in Dopamine
WHAT IS PRL-8-53
PRL 8 53 is in the family of nootropic chemicals. The term ‘nootropics’ originally described chemicals with precise criteria, however now it describes any natural or synthetic substance which might positively affect our mental abilities, especially memory and cognition. It is a favorite research chemical of mine, as this nootropic helps sufficiently in the agility of the mind.
PRL 8 53 generates a nootropic effect in healthy individuals. PRL-8-53 has intrigued the nootropic community for decades.
A professor discovered PRL-8-53 from Creighton University in 1973, Nicolaus Hensl, who then patented it a couple of years later.
Only one human study on PRL-8-53 was conducted and funded by the Professor in over 40 years. The results suggest that a single dose of PRL-8-53 could improve short-term memory by more than 200%.
The double-blind human study used word committal to memory as a gauge, examining the participants’ skill to remember a list of 12 one-syllable words, first to determine a baseline and then again after consuming PRL-8-53 or a placebo. The subjects were tested on their capacity to recall the words 24 hours after examining them and then once again one week afterward.
The study outcomes indicate that applicants who had higher baseline scores showed the least improvement after ingesting PRL-8-53. In contrast, subjects who had demonstrated lower initial memory or over 30 years of age showed significant recall improvement.
Hensl described the effect on the older participants as follows:
“This group was age 30 or older. As might be expected, routine memory did not come as easily to this group as the younger students—average memory after 24 hours when on placebo was just under three words out of a possible 12. The average preservation after one week was two words. However, when learning after drug administration, the same subjects maintained an average of 5.85 words after 24 hours and 5.25 words following one week. Again the growths were statistically significant. The enhancement expressed in percent of placebo performance was 108% for the 24-hour test and 152% for the one-week recall.”
This study, conducted in 1978, was done on human volunteers aged 24 to 86. No adverse side effects were observed in the human study.
To this day the mechanism of action is still not quite understood.
IS PRL-8-53 SAFE?
Preliminary rodent evidence suggests PRL-8-53 long-term is safe to use as a dietary supplement; however, since this compound is a synthetic substance, all proof of its effects coming from studies, only funded by the patent holder- could be possibly questioned.
The Professor did indicate that older volunteers saw the most significant benefit, so this supports the idea of dopamine modulation playing a substantial role in PRL 8 53’s effects.
Apomorphine is a dopamine agonist and causes obsessive gnawing in rats. Combining PRL-8-53 with apomorphine was to be used to evaluate the dopaminergic effect of PRL-8-53 via altering in gnawing behavior. PRL-8-53 at 4mg/kg improved apomorphine-induced gnawing in rats and was also successful in improving trained avoidance learning, implying that PRL-8-53 is a dopamine agonist.
What is the meaning of agonist and antagonist?
An agonist is a molecule adept at binding to and functionally triggering a point. The target is inherently a metabotropic and/or ionotropic receptor. An antagonist is a molecule that unites to a focus and prevents other molecules (e.g., agonists) from attaching.
BRAIN EFFECTS ON PRL-8-53
“The drug is not a stimulant, and in the experimental animal, toxicity appears only after it is given a dose more than one thousand times as large as the projected human dose. In summary, we now have a potentially useful drug that will boost a specific chemical system in the brain, the cholinergic system, and thereby improve our ability to recall, to retrieve information from a pre-existing information pool.”
PRL 853's shows cholinergic properties and potentiates dopamine while partially inhibiting serotonin. PRL-8-53 reverses catatonic and ptotic effects of reserpine.
Research shows that PRL 8 53 increases acetylcholine activity, and since it’s a neurotransmitter, it plays a role in memory and cognition. Another apparent effect is that PRL-8-53 seems to inhibit serotonin production- causing a decrease in feelings of anxiety, assisting in the relief of insomnia, and suppressing depression.
PRL-8-53 is one of the most promising nootropics on the market-derived from benzoic acid and phenylmethylamine. PRL 8-53 nootropic does occur in some of our regular food choices, including dairy products or berries.
For anyone wanting to increase their cognitive function, some doctors believe the right nootropics can help you think clearly and sharply, as well as reducing age-related cognitive decline. Anecdotal evidence proves it.
Nootropics for sale online for the ultimate best purity and potency. Buy PRL 853, our price and quality speak volumes. Third-party lab tested.
We ship Monday through Friday. All orders are shipped through Canada Post. All order funds received before 3:00 pm MNT for items will be shipped the same day. All order funds received after 3:00 pm MNT on business days will ship the next business day. Once you have the tracking number, please permit it to enter the mail system before checking.
We create every effort to maintain the highest levels of superior customer service. Our ultimate goal at 99PURiTY is to create lifelong clients and we will do all in our capacity to ensure that your experience with us makes you want to shop with us all over again.
If your order is scanned as delivered but you have not received it, please contact us within 48 hours of delivery confirmation to start a criminal theft investigation. If it goes longer than 48 hours before we receive contact, we cannot investigate this matter. This will void any reship possibility on our part.
Yes, we ship from Canada to Australia, Europe, and United States. Numerous restrictions and policies govern the international transportation of research chemical products. We do our best to make sure it gets to you, or we will reship. We have had 100% success rate.
We accept the following payment methods:
E-Transfer | Wise.com (Formerly Transferwise) | Bitcoin
- For Candian bank accounts only
- Details will be sent on the order confirmation.
Credit Card/ Debit
How to Use Wise (formerly transferwise.com)
- Create a Wise account on wise.com
- On the top sidebar, Click Send Money, and then Add Payment Method.
- Click Credit/Debit Card.
- Enter your card’s information.
- Once the card is confirmed and you are verified, you can place an order on our website and receive our payment details.
Wise Works with:
- Debit Card
- Credit Card
How to Set up a wallet using Coinbase
Bitcoin Works with:
- Create a Coinbase account.
- Go to Settings, then Payment Methods, and then click Add Payment Method.
- Click Credit/Debit Card.
- Enter your card’s information.
- Once the card is confirmed, you can go to Buy/Sell and buy your bitcoins.
- The bitcoins will be sent to your Coinbase wallet.
- Debit Card
- Checking Account
If you get any troubles with your order, please contact us.
If we receive the wrong address given for delivery, please contact the individual at the address; the parcel can be sent back to us unopened before taking it to the post office and writing a “refused, return to sender.” We cannot cover wrong address re-shipments.
Please make sure you input the address correctly. please go into your account settings and double-check to make sure the address is perfect, as well as the apartment or suite number and buzzer number, if required for entry.
To be eligible for a refund, your parcel must NOT be in processing or must NOT still be in transit. You will receive email updates, or we will refund upon return of the items.
We do not accept returns after 30 days.
Once it has been received at the warehouse, we will refund your payment method. Shipping and return shipment costs (if any) are non-refundable.
All parcels are shipped securely and in a fashion that guarantees safe entrance. But for any reason, this is not the case, then please email us then we will work along with you to get the problem fixed.
If merchandise is missing from your order, please contact us, and once we verify the legitimacy of the claim before we send the missing item(s) to you. All purchases are documented and are photographed before shipment to avoid any fraudulent claims.